Vrijdag 21 augustus 2015
Gewrichtskraakbeen letsel kan pijn, vochtophoping in het gewricht en het op slot zetten van het gewricht tot gevolg hebben. Oorzaak is voornamelijk gerelateerd aan sportieve activiteiten en komt vaak voor met gewrichtsletsel. Dit proefschrift gaat in op: Chapter 1: General introduction Chapter 2: Aims of this thesis Chapter 3: Development of partial-thickness articular cartilage injury in a rabbit model Chapter 4: One intra-articular injection of hyaluronan prevents cell deatch and improves cell metabolism in a model of injured articular cartilage in the rabbit Chapter 5: PEOT/PBT based scaffolds with low mechanical properties improve cartilage repair tissue formation in osteochondral effects Chapter 6: Human periosteum-derived cells from elderly patiens as source for cartilage tissue engineering? Chapter 7: Assessing infection risk in implanted tissue-engineered devices Chapter 8: Hydrophobicity as a design criterion for polymer scaffolds in bone tissue engineering Chapter 9: General discussion